Manager, Regulatory Affairs
Full time
at Fresenius medical care
in
Malaysia
Posted on April 29, 2024
Job details
Key Responsibilities / Accountabilities: Pharmacovigilance
- Collection of local AEs / ADRs
- Contact point for local regulatory authorities
- Forwarding of case reports and other important safety information to CDS
- Following up on case reports for any missing information or upon request of CDS
- E-mail or paper-based submission of ICSRs to authorities who do not allow electronic reporting (Non-EU countries)
- Quarterly reconciliation of case reports
- Screening of local literature
- PSUR submission to local authorities
- Local implementation of RMP commitments
- Local implementation of safety label changes in collaboration with CDRA
- Review of applicable local PV legislation or regulation
- Forwarding of safety relevant Health Authority requests to CDS
- Exchange of actions taken for safety reasons
- Processing of local CAPA
- Plan, review and recommend the best regulatory strategy for Pharmaceutical and medical Device submissions, including regulatory timelines, during the planning phase for pipeline products of assigned portfolio based on regulatory expertise with country regulations & MOH processes.
- Manage and ensure the country Regulatory Plans are in alignment with Product Teams & Area strategies, and the country’s business plan.
- Coordinates the process with other functional members of the affiliate, sites and corporate to ensure timely availability of required documents and other requirements for dossier preparation.
- Active participation in cross-functional teams within the affiliate and provide regulatory expertise and insight to ensure regulatory timelines are met or improved.
- Prepare a quality regulatory dossier and submit within the planned affiliate timelines for new product submissions, line extensions, variations etc.
- Activities include: Request and obtain the various regulatory items needed for the local submission Prepare/format the dossier to ensure it meets local requirements Implement the submission and archive appropriately
- Gain Malaysia MoH approvals to meet the affiliate product launch plans and ensure product maintenance.
- Activities include: Provide quality responses to the Ministry of Health (MOH) by the due date Complete regulatory approval process and gain product licenses Communicate Product approval Archive submission dossier and approval documents Track post approval commitment, if any Perform regulatory responsibilities related packaging development Ensure the local label creation and packaging development will meet local and corporate criteria and supports the business needs
- Prepare periodic Regulatory Report of actual submissions and approval
- Take appropriate actions to maintain all local marketed products in compliance with local and corporate regulatory requirements and country acts, regulations, codes, and standards or guidelines [eg. Change control for medical device, all aspects of labelling (Product Information and packaging development); label change management; chemistry and manufacturing commitments that are registered with the MoH]
- Conduct periodic compliance self-audit to identify potential compliance issues
- Perform activities related to pharmacovigilance (PhV) and materiovigilance according to Corporate and if applicable, by local regulations.
- Ensure that all functions perform in accordance with the Standard Operating Procedures to meet the Good Distribution Guidelines
- Co-ordinate the implementation and maintenance of Quality Management Systems including establishing and maintaining regulatory compliance system, coordinating management review and performing relevant audits (e.g. internal audits and vendor audits)
- Take corrective actions plans based on regulatory and pharmacovigilance audit findings
- Regulatory Customer Relations Establish relationship with key regulatory officials to influence regulators to foster positive regulatory environment for business and research.
- Regulatory Environment Changes Keep updated with current local regulations and MoH organizational structure and potential changes that will impact the business environment and communicate appropriately to involved or affected parties.
- Influence Strategy Supports the development and implementation of the established external regulatory influence strategy.
- Trade Association- Work with Trade Associations in Malaysia on different Regulatory issues and share company position on different topics.
- Learn and understand the local affiliate organization and functions.
- Build functional partnership and credibility to maximize regulatory value in support of business decisions.
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Well, look no further; you've come to the right place!<br> <br> Our easy-to-follow Hazard Analysis & Critical Control Point (HACCP): Level 3 Training will provide you with all the deep knowledge and insight you need to know about this topic. This comprehensive course has been broken down into several manageable modules, which we believe will assist you to easily grasping each concept - from the fundamental to the more advanced aspects of the ;<br> <br> Learn the most in-demand skills from the safety & comfort of your home. 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Well, look no further; you've come to the right place!<br> <br> Our easy-to-follow Hazard Analysis & Critical Control Point (HACCP): Level 3 Training will provide you with all the deep knowledge and insight you need to know about this topic. This comprehensive course has been broken down into several manageable modules, which we believe will assist you to easily grasping each concept - from the fundamental to the more advanced aspects of the ;<br> <br> Learn the most in-demand skills from the safety & comfort of your home. 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Submissions and Approvals </b> </p> <p><u> a) Dossier Preparation </u> </p> <ul><li> Prepare a quality regulatory dossier and submit within the planned affiliate timelines for new product submissions, line extensions, variations etc. </li><li> Activities include: <p> Request and obtain the various regulatory items needed for the local submission </p><p> Prepare/format the dossier to ensure it meets local requirements </p><p> Implement the submission and archive appropriately </p></li> </ul> <p><u> b) Gain Regulatory Approval </u> </p> <ul><li> Gain Malaysia MoH approvals to meet the affiliate product launch plans and ensure product maintenance. </li> </ul> <ul><li> Activities include: <p> Provide quality responses to the Ministry of Health (MOH) by the due date </p><p> Complete regulatory approval process and gain product licenses </p><p> Communicate Product approval </p><p> Archive submission dossier and approval documents </p><p> Track post approval commitment, if any </p><p> Perform regulatory responsibilities related packaging development </p><p> Ensure the local label creation and packaging development will meet local and corporate criteria and supports the business needs </p></li> </ul> <p><u> c) Metrics Review </u> </p> <ul><li> Prepare periodic Regulatory Report of actual submissions and approval </li> </ul> <p><b>4. Regulatory Compliance </b> </p> <p><u> a) Compliance Maintenance </u> </p> <ul><li> Take appropriate actions to maintain all local marketed products in compliance with local and corporate regulatory requirements and country acts, regulations, codes, and standards or guidelines [eg. Change control for medical device, all aspects of labelling (Product Information and packaging development); label change management; chemistry and manufacturing commitments that are registered with the MoH]</li><li> Conduct periodic compliance self-audit to identify potential compliance issues </li><li> Perform activities related to pharmacovigilance (PhV) and materiovigilance according to Corporate and if applicable, by local regulations. </li><li> Ensure that all functions perform in accordance with the Standard Operating Procedures to meet the Good Distribution Guidelines </li><li> Co-ordinate the implementation and maintenance of Quality Management Systems including establishing and maintaining regulatory compliance system, coordinating management review and performing relevant audits (e.g. internal audits and vendor audits)</li><li> Take corrective actions plans based on regulatory and pharmacovigilance audit findings </li> </ul> <p>5. <b> Regulatory Influence </b> </p> <p><u> 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